Kamagra 100 mg belongs to the group of drugs classified to treat ED. This drug has a mild effect while activating the natural mechanism associated with erectile function. As such, this drug does not affect native hormonal balance, does not interfere with normal metabolism, and does not cause addiction. The most famous analog of this drug is Viagra.
Kamagra 100 mg is generic Viagra. This drug is not subject to patent restrictions, which reduces its retail cost. Despite the low cost, the pharmacological composition and action of Kamagra 100 mg completely mirror the original medicine.
Compared with the brand name drug Viagra (i.e., 100 mg of sildenafil, which is considered the standard), Kamagra 100 mg contains the same amount of active ingredient at a much lower price. Noticeable effects of Kamagra 100 mg occur even as low as 25 mg doses. Therefore, in most cases, one tablet of Kamagra 100 mg can be divided into four parts.
The high level of content of the active ingredient contained within Kamagra 100 mg allows users to stretch the use of one package for a long time. In addition, this drug formulation is perfect for treating severe cases of ED or in cases where there is high tolerance to the main active ingredient of the drug.
The pharmacological effect of Kamagra 100 mg is explained by its ability to bind and suppress the action of the natural regulator of blood flow within the penis, which is the PDE5 enzyme. The action of sildenafil relative to this enzyme is several hundred times greater than all substances known to science.
Blocking PDE5 provokes an increase in the level of free nitric oxide within blood vessels. Smooth muscle relaxation leads to significant blood flow to the penis and achievement of an erection. The effects caused by sildenafil are natural. This drug does not affect either the hormonal or metabolic systems of the body.
Sildenafil absorption begins in the small intestine from which it is able to quickly enter the bloodstream where it can bind proteins. The active concentration of sildenafil can be reached 60 minutes after ingestion. Sildenafil is metabolized and excreted by the liver. A small amount (up to 15%) enters the kidneys and is excreted in the urine unchanged. The total pharmacological effect of sildenafil lasts an average of 4 hours. Peak activity of sildenafil is two hours after the onset of action, which is followed by a decline and a gradual weakening of the erection.
Pharmacological efficacy and safety of Kamagra 100mg have been confirmed via clinical trials. More than 80% of patients that take sildenafil at dosages of 75 to 100 mg daily noted increased improvement in erectile function in the absence of negative side effects.
Indications for use
Kamagra 100 mg is recommended for men suffering from severe ED. The drug is especially effective in cases where ED is vascular in origin. In such cases, Kamagra 100 mg can be prescribed even to elderly patients. The effectiveness of Kamagra 100 mg is only observed in the concurrent presence of sexual stimulation.
Mode of application
Kamagra 100 mg is taken orally, roughly about a half an hour prior to having sexual intercourse. This drug easily binds fats where it can lose up to 50% of its total bioavailability. Therefore, Kamagra 100 mg should be taken on an empty stomach for optimal effectiveness.
The recommended dosage of Kamagra is from 50 to 100 mg, which should only occur once per day. In general, one tablet of Kamagra 100 mg should be divided into two parts. 50 mg of the active ingredient contained within Kamagra is adequate for inducing a noticeable effect. In cases where 50 mg is not effective, the dosage can be increased to the full 100 mg for the next time.
Prior to taking Kamagra 100 mg, it is important to undergo a full medical examination to ensure proper health and identify if there are any allergies that may cause negative side effects. This is particularly important for potential users who are over 60 years of age as well as patients suffering from liver disease. In such cases, a single dosage should be reduced to 25 mg per day. One tablet of Kamagra 100 mg can be divided into 4 or 5 parts.
Consumption of sildenafil in any form and dosage is strictly contraindicated in the presence of serious diseases of the cardiovascular system including the following:
• Ischemic heart disease of any stage;
• Heart failure;
• Postponed myocardial infarction with the risk of recurrence;
• Postponed stroke;
• Stage 2 or 3 Hypertension;
Contrary to popular belief, sildenafil demonstrates no significant effect on the cardiovascular system. Noted contraindications are based on the fact that sexual activity in itself significantly increases the risk of complications.
In addition, it is also important to note that Kamagra increases the activity of all nitrate-based drugs, including nitroglycerin, amyl nitrite, and gluconate. If it is necessary to take these drugs, the dosage of Kamagra should be minimal (from 25 to 50 mg per day).
In the presence of any vascular or anatomical abnormalities associate with the structure of the penis (e.g., fibrosis of the cavernous body, vascular malformations, etc.), it is better to refrain from using Kamagra 100 mg. The consumption of Kamagra 100 mg should also be limited in cases of liver disease (including cirrhosis), severe renal failure, peptic ulcer, and/or low coagulation factor.
If there are known allergies to Kamagra 100 mg, this drug should not be taken in any dose. This drug should also not be taken by individuals less than 18 years of age or in women of any age.
Possible side effects
The most common complications associated with taking Kamagra 100 mg are a feeling of heat, redness of the face, headache, and dizziness. However, clinical trial results suggest that these complications occur only in 10% of patients, which is not dependent on dosage. Some patients have also reported nasal congestion and slight visual disturbances (i.e. symptoms that pass independently within an hour after administration of Kamagra 100 mg.
More serious side effects are relatively rare (~2% or fewer patients), which may include:
• Allergic reactions;
• Slowed heart rate;
• Low blood pressure;
• Nose bleeds;
• Puffiness of the extremities;
• Chills, sweating;
• Frequent urge to urinate;
If any the aforementioned symptoms develop after taking Kamagra 100 mg, it is important to seek immediate medical attention and stop taking the drug.
Significant over-consumption of Kamagra (>500 mg at one time) will lead to an increased risk of side effects at heightened severity.
Terms and conditions of storage
In contrast to brand name drugs such as Viagra, generic forms (including Kamagra 100 mg) can be purchased without such restrictions. The shelf life of Kamagra 100 mg is no more than two years from the date of manufacture. Kamagra 100 mg should be stored in its original packaging in a cool dry location. After the expiration date, Kamagra 100 mg should not be used under any circumstance.